Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures

The spatiotemporal transmission of pathological tau in the brain is characteristic of Alzheimer's disease. Release of both soluble and abnormal tau species from healthy neurons is increased upon stimulation of neuronal activity. It is not yet understood whether the mechanisms controlling solubl...

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Vydáno v:Cell Death Dis
Hlavní autoři: Croft, Cara L, Wade, Matthew A, Kurbatskaya, Ksenia, Mastrandreas, Pavlina, Hughes, Martina M, Phillips, Emma C, Pooler, Amy M, Perkinton, Michael S, Hanger, Diane P, Noble, Wendy
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386587/
https://ncbi.nlm.nih.gov/pubmed/28300838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.97
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