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Inhibition of glycogen synthase kinase-3 by BTA-EG(4) reduces tau abnormalities in an organotypic brain slice culture model of Alzheimer’s disease

Organotypic brain slice culture models provide an alternative to early stage in vivo studies as an integrated tissue system that can recapitulate key disease features, thereby providing an excellent platform for drug screening. We recently described a novel organotypic 3xTg-AD mouse brain slice cult...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Croft, Cara L., Kurbatskaya, Ksenia, Hanger, Diane P., Noble, Wendy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547074/
https://ncbi.nlm.nih.gov/pubmed/28785087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07906-1
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