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Inhibition of glycogen synthase kinase-3 by BTA-EG(4) reduces tau abnormalities in an organotypic brain slice culture model of Alzheimer’s disease

Organotypic brain slice culture models provide an alternative to early stage in vivo studies as an integrated tissue system that can recapitulate key disease features, thereby providing an excellent platform for drug screening. We recently described a novel organotypic 3xTg-AD mouse brain slice cult...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Croft, Cara L., Kurbatskaya, Ksenia, Hanger, Diane P., Noble, Wendy
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547074/
https://ncbi.nlm.nih.gov/pubmed/28785087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07906-1
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