Investigating cell death mechanisms in amyotrophic lateral sclerosis using transcriptomics

por Heath, Paul R., Kirby, Janine, Shaw, Pamela J.
Publicado 2013

The genetics of amyotrophic lateral sclerosis: current insights

por Alsultan, Afnan A, Waller, Rachel, Heath, Paul R, Kirby, Janine
Publicado en Degener Neurol Neuromuscul Dis (2016)

Profiling microRNAs in uncomplicated pregnancies: Serum vs. plasma

por Parker, Victoria L., Gavriil, Eleftherios, Marshall, Benjamin, Pacey, Allan, Heath, Paul R.
Publicado en Biomed Rep (2021)

Neuronal dark matter: the emerging role of microRNAs in neurodegeneration

por Goodall, Emily F., Heath, Paul R., Bandmann, Oliver, Kirby, Janine, Shaw, Pamela J.
Publicado 2013

Microarray Analysis of the Cellular Pathways Involved in the Adaptation to and Progression of Motor Neuron Injury in the SOD1 G93A Mouse Model of Familial ALS

por Ferraiuolo, Laura, Heath, Paul R., Holden, Hazel, Kasher, Paul, Kirby, Janine, Shaw, Pamela J.
Publicado en J Neurosci (2007)

Dysregulation of astrocyte–motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis

por Ferraiuolo, Laura, Higginbottom, Adrian, Heath, Paul R., Barber, Sian, Greenald, David, Kirby, Janine, Shaw, Pamela J.
Publicado 2011

Small RNA Sequencing of Sporadic Amyotrophic Lateral Sclerosis Cerebrospinal Fluid Reveals Differentially Expressed miRNAs Related to Neural and Glial Activity

por Waller, Rachel, Wyles, Matthew, Heath, Paul R., Kazoka, Mbombe, Wollff, Helen, Shaw, Pamela J., Kirby, Janine
Publicado en Front Neurosci (2018)

Comparison and optimisation of microRNA extraction from the plasma of healthy pregnant women

por Parker, Victoria L., Cushen, Bryony F., Gavriil, Eleftherios, Marshall, Benjamin, Waite, Sarah, Pacey, Allan, Heath, Paul R.
Publicado en Mol Med Rep (2021)

Regulation of Neutrophil Senescence by MicroRNAs

por Ward, Jon R., Heath, Paul R., Catto, James W., Whyte, Moira K. B., Milo, Marta, Renshaw, Stephen A.
Publicado 2011

Comparison of Blood RNA Extraction Methods Used for Gene Expression Profiling in Amyotrophic Lateral Sclerosis

por Bayatti, Nadhim, Cooper-Knock, Johnathan, Bury, Joanna J., Wyles, Matthew, Heath, Paul R., Kirby, Janine, Shaw, Pamela J.
Publicado 2014

Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis

por Shelkovnikova, Tatyana A., Kukharsky, Michail S., An, Haiyan, Dimasi, Pasquale, Alexeeva, Svetlana, Shabir, Osman, Heath, Paul R., Buchman, Vladimir L.
Publicado en Mol Neurodegener (2018)

Transcriptome Analysis of Gene Expression Provides New Insights into the Effect of Mild Therapeutic Hypothermia on Primary Human Cortical Astrocytes Cultured under Hypoxia

por Salman, Mootaz M., Kitchen, Philip, Woodroofe, M. Nicola, Bill, Roslyn M., Conner, Alex C., Heath, Paul R., Conner, Matthew T.
Publicado en Front Cell Neurosci (2017)

Luzp4 defines a new mRNA export pathway in cancer cells

por Viphakone, Nicolas, Cumberbatch, Marcus G., Livingstone, Michaela J., Heath, Paul R., Dickman, Mark J., Catto, James W., Wilson, Stuart A.
Publicado en Nucleic Acids Res (2015)

Pulsatile exposure to simulated reflux leads to changes in gene expression in a 3D model of oesophageal mucosa

por Green, Nicola H, Nicholls, Zoe, Heath, Paul R, Cooper-Knock, Jonathan, Corfe, Bernard M, MacNeil, Sheila, Bury, Jonathan P
Publicado en Int J Exp Pathol (2014)

Neutrophil-Derived Microvesicle Induced Dysfunction of Brain Microvascular Endothelial Cells In Vitro

por Ajikumar, Anjana, Long, Merete B., Heath, Paul R., Wharton, Stephen B., Ince, Paul G., Ridger, Victoria C., Simpson, Julie E.
Publicado en Int J Mol Sci (2019)

Alpha-synuclein mRNA expression in oligodendrocytes in MSA

por Asi, Yasmine T, Simpson, Julie E, Heath, Paul R, Wharton, Stephen B, Lees, Andrew J, Revesz, Tamas, Houlden, Henry, Holton, Janice L
Publicado en Glia (2014)

The Effect of SOD1 Mutation on Cellular Bioenergetic Profile and Viability in Response to Oxidative Stress and Influence of Mutation-Type

por Richardson, Katie, Allen, Scott P., Mortiboys, Heather, Grierson, Andrew J., Wharton, Stephen B., Ince, Paul G., Shaw, Pamela J., Heath, Paul R.
Publicado 2013

Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 (G93A) mouse model of amyotrophic lateral sclerosis

por Baker, David J., Blackburn, Daniel J., Keatinge, Marcus, Sokhi, Dilraj, Viskaitis, Paulius, Heath, Paul R., Ferraiuolo, Laura, Kirby, Janine, Shaw, Pamela J.
Publicado en Front Cell Neurosci (2015)

Integrative molecular characterization of pediatric spinal ependymoma: the UK Children’s Cancer and Leukaemia Group study

por Ahmad, Omar, Chapman, Rebecca, Storer, Lisa C, Luo, Li, Heath, Paul R, Resar, Linda, Cohen, Kenneth J, Grundy, Richard G, Lourdusamy, Anbarasu
Publicado en Neurooncol Adv (2021)

Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGF(δ/δ )mouse model of amyotrophic lateral sclerosis

por Brockington, Alice, Heath, Paul R, Holden, Hazel, Kasher, Paul, Bender, Florian LP, Claes, Filip, Lambrechts, Diether, Sendtner, Michael, Carmeliet, Peter, Shaw, Pamela J
Publicado 2010