Pulsatile exposure to simulated reflux leads to changes in gene expression in a 3D model of oesophageal mucosa

Oesophageal exposure to duodenogastroesophageal refluxate is implicated in the development of Barrett's metaplasia (BM), with increased risk of progression to oesophageal adenocarcinoma. The literature proposes that reflux exposure activates NF-κB, driving the aberrant expression of intestine-s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Exp Pathol
Main Authors: Green, Nicola H, Nicholls, Zoe, Heath, Paul R, Cooper-Knock, Jonathan, Corfe, Bernard M, MacNeil, Sheila, Bury, Jonathan P
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351858/
https://ncbi.nlm.nih.gov/pubmed/24713057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12083
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados