Neutrophil-Derived Microvesicle Induced Dysfunction of Brain Microvascular Endothelial Cells In Vitro

The blood-brain barrier (BBB), composed of brain microvascular endothelial cells (BMEC) that are tightly linked by tight junction (TJ) proteins, restricts the movement of molecules between the periphery and the central nervous system. Elevated systemic levels of neutrophils have been detected in pat...

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Udgivet i:Int J Mol Sci
Main Authors: Ajikumar, Anjana, Long, Merete B., Heath, Paul R., Wharton, Stephen B., Ince, Paul G., Ridger, Victoria C., Simpson, Julie E.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834153/
https://ncbi.nlm.nih.gov/pubmed/31652502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205227
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