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Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGF(δ/δ )mouse model of amyotrophic lateral sclerosis

BACKGROUND: Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen that stimulates vasculogenesis. It has also been shown to act as a neurotrophic factor in vitro and in vivo. Deletion of the hypoxia response element of the promoter region of the gene encoding VEGF in mice causes a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Brockington, Alice, Heath, Paul R, Holden, Hazel, Kasher, Paul, Bender, Florian LP, Claes, Filip, Lambrechts, Diether, Sendtner, Michael, Carmeliet, Peter, Shaw, Pamela J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861063/
https://ncbi.nlm.nih.gov/pubmed/20346106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-203
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