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Lemur tyrosine kinase-2 signalling regulates kinesin light chain-2 phosphorylation and binding of Smad2 cargo

A recent genome wide association study identified the gene encoding lemur tyrosine kinase-2 (LMTK2) as a susceptibility gene for prostate cancer. The identified genetic alteration is within intron 9 but the mechanisms by which LMTK2 may impact upon prostate cancer are not clear because the functions...

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Detalhes bibliográficos
Main Authors: Manser, Catherine, Guillot, Florence, Vagnoni, Alessio, Davies, Jennifer, Lau, Kwok-Fai, McLoughlin, Declan M., De Vos, Kurt J., Miller, Christopher C.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272475/
https://ncbi.nlm.nih.gov/pubmed/21996745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.437
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