A comprehensive assessment of the SOD1(G93A) low-copy transgenic mouse, which models human amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that results in the death of motor neurons in the brain and spinal cord. The disorder generally strikes in mid-life, relentlessly leading to paralysis and death, typically 3–5 years after diagnosis. No effective treatmen...

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Bibliographische Detailangaben
Hauptverfasser: Acevedo-Arozena, Abraham, Kalmar, Bernadett, Essa, Shafa, Ricketts, Thomas, Joyce, Peter, Kent, Rosie, Rowe, Claire, Parker, Andy, Gray, Anna, Hafezparast, Majid, Thorpe, Julian R., Greensmith, Linda, Fisher, Elizabeth M. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Limited 2011
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Resource Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180233/
https://ncbi.nlm.nih.gov/pubmed/21540242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.007237
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