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Evaluation of Neuropathological Features in the SOD1-G93A Low Copy Number Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) still depicts an incurable and devastating disease. Drug development efforts are mostly based on superoxide dismutase 1 gene (SOD1)-G93A mice that present a very strong and early phenotype, allowing only a short time window for intervention. An alternative mouse m...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Molnar-Kasza, Agnes, Hinteregger, Barbara, Neddens, Joerg, Rabl, Roland, Flunkert, Stefanie, Hutter-Paier, Birgit
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264456/
https://ncbi.nlm.nih.gov/pubmed/34248499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.681868
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