Evaluation of Neuropathological Features in the SOD1-G93A Low Copy Number Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) still depicts an incurable and devastating disease. Drug development efforts are mostly based on superoxide dismutase 1 gene (SOD1)-G93A mice that present a very strong and early phenotype, allowing only a short time window for intervention. An alternative mouse m...

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Bibliografiske detaljer
Udgivet i:Front Mol Neurosci
Main Authors: Molnar-Kasza, Agnes, Hinteregger, Barbara, Neddens, Joerg, Rabl, Roland, Flunkert, Stefanie, Hutter-Paier, Birgit
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Molecular Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264456/
https://ncbi.nlm.nih.gov/pubmed/34248499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.681868
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