Evaluation of Neuropathological Features in the SOD1-G93A Low Copy Number Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) still depicts an incurable and devastating disease. Drug development efforts are mostly based on superoxide dismutase 1 gene (SOD1)-G93A mice that present a very strong and early phenotype, allowing only a short time window for intervention. An alternative mouse m...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Autores principales: Molnar-Kasza, Agnes, Hinteregger, Barbara, Neddens, Joerg, Rabl, Roland, Flunkert, Stefanie, Hutter-Paier, Birgit
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264456/
https://ncbi.nlm.nih.gov/pubmed/34248499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.681868
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