FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis

INTRODUCTION: FUS/TLS is an RNA-binding protein whose genetic mutations or pathological inclusions are associated with neurological diseases including amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration, and essential tremor (ET). It is unclear whether their pathogenesis is mediat...

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Dades bibliogràfiques
Publicat a:Acta Neuropathol Commun
Autors principals: Kino, Yoshihiro, Washizu, Chika, Kurosawa, Masaru, Yamada, Mizuki, Miyazaki, Haruko, Akagi, Takumi, Hashikawa, Tsutomu, Doi, Hiroshi, Takumi, Toru, Hicks, Geoffrey G, Hattori, Nobutaka, Shimogori, Tomomi, Nukina, Nobuyuki
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408580/
https://ncbi.nlm.nih.gov/pubmed/25907258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0202-6
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