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FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis

INTRODUCTION: FUS/TLS is an RNA-binding protein whose genetic mutations or pathological inclusions are associated with neurological diseases including amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration, and essential tremor (ET). It is unclear whether their pathogenesis is mediat...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Kino, Yoshihiro, Washizu, Chika, Kurosawa, Masaru, Yamada, Mizuki, Miyazaki, Haruko, Akagi, Takumi, Hashikawa, Tsutomu, Doi, Hiroshi, Takumi, Toru, Hicks, Geoffrey G, Hattori, Nobutaka, Shimogori, Tomomi, Nukina, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408580/
https://ncbi.nlm.nih.gov/pubmed/25907258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0202-6
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