Cyclic AMP compartments and signaling specificity: Role of cyclic nucleotide phosphodiesterases

Por Conti, Marco, Mika, Delphine, Richter, Wito
Publicado em 2014

A CaMKII/PDE4D negative feedback regulates cAMP signaling

Por Mika, Delphine, Richter, Wito, Conti, Marco
Publicado no Proc Natl Acad Sci U S A (2015)

Splice variants of the cyclic nucleotide phosphodiesterase PDE4D are differentially expressed and regulated in rat tissue

Por Richter, Wito, Jin, S.-L. Catherine, Conti, Marco
Publicado em 2005

PDE4 as a target for cognition enhancement

Por Richter, Wito, Menniti, Frank S., Zhang, Han-Ting, Conti, Marco
Publicado em 2013

β(1)-adrenergic receptor antagonists signal via PDE4 translocation

Por Richter, Wito, Mika, Delphine, Blanchard, Elise, Day, Peter, Conti, Marco
Publicado em 2013

Inactivation of Multidrug Resistance Proteins Disrupts Both Cellular Extrusion and Intracellular Degradation of cAMP

Por Xie, Moses, Rich, Thomas C., Scheitrum, Colleen, Conti, Marco, Richter, Wito
Publicado em 2011

Critical Role of PDE4D in β(2)-Adrenoceptor-dependent cAMP Signaling in Mouse Embryonic Fibroblasts

Por Bruss, Matthew D., Richter, Wito, Horner, Kathleen, Jin, S.-L. Catherine, Conti, Marco
Publicado em 2008

PDE4B mediates local feedback regulation of β(1)-adrenergic cAMP signaling in a sarcolemmal compartment of cardiac myocytes

Por Mika, Delphine, Richter, Wito, Westenbroek, Ruth E., Catterall, William A., Conti, Marco
Publicado em 2014

Roles of GRK and PDE4 Activities in the Regulation of β(2) Adrenergic Signaling

Por Xin, Wenkuan, Tran, Tuan M., Richter, Wito, Clark, Richard B., Rich, Thomas C.
Publicado em 2008

Conserved expression and functions of PDE4 in rodent and human heart

Por Richter, Wito, Xie, Moses, Scheitrum, Colleen, Krall, Judith, Movsesian, Matthew A., Conti, Marco
Publicado em 2010

PDE4D and PDE4B Function in Distinct Subcellular Compartments in Mouse Embryonic Fibroblasts

Por Blackman, Brigitte E., Horner, Kathleen, Heidmann, Julia, Wang, Dan, Richter, Wito, Rich, Thomas C., Conti, Marco
Publicado em 2011

The Upstream Conserved Regions (UCRs) Mediate Homo- and Hetero-oligomerization of Type 4 Cyclic Nucleotide Phosphodiesterases (PDE4s)

Por Xie, Moses, Blackman, Brigitte, Scheitrum, Colleen, Mika, Delphine, Blanchard, Elise, Lei, Tao, Conti, Marco, Richter, Wito
Publicado no Biochem J (2014)

Estimating the magnitude of near-membrane PDE4 activity in living cells

Por Xin, Wenkuan, Feinstein, Wei P., Britain, Andrea L., Ochoa, Cristhiaan D., Zhu, Bing, Richter, Wito, Leavesley, Silas J., Rich, Thomas C.
Publicado no Am J Physiol Cell Physiol (2015)

Shank2 mutant mice display a hypersecretory response to cholera toxin

Por Jung, Eun Suk, Park, Joonhee, Gee, Heon Yung, Jung, Jinsei, Noh, Shin Hye, Lee, Jung-Soo, Richter, Wito, Namkung, Wan, Lee, Min Goo
Publicado em 2014

Decreased expression and activity of cAMP phosphodiesterases in cardiac hypertrophy and its impact on β-adrenergic cAMP signals

Por Abi-Gerges, Aniella, Richter, Wito, Lefebvre, Florence, Mateo, Philippe, Varin, Audrey, Heymes, Christophe, Samuel, Jane-Lise, Lugnier, Claire, Conti, Marco, Fischmeister, Rodolphe, Vandecasteele, Grégoire
Publicado em 2009

Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias

Por Lehnart, Stephan E., Wehrens, Xander H.T., Reiken, Steven, Warrier, Sunita, Belevych, Andriy E., Harvey, Robert D., Richter, Wito, Jin, S.-L. Catherine, Conti, Marco, Marks, Andrew R.
Publicado em 2005

Anchored PDE4 regulates chloride conductance in wild-type and ΔF508-CFTR human airway epithelia

Por Blanchard, Elise, Zlock, Lorna, Lao, Anna, Mika, Delphine, Namkung, Wan, Xie, Moses, Scheitrum, Colleen, Gruenert, Dieter C., Verkman, Alan S., Finkbeiner, Walter E., Conti, Marco, Richter, Wito
Publicado em 2014

Signaling from β(1)- and β(2)-adrenergic receptors is defined by differential interactions with PDE4

Por Richter, Wito, Day, Peter, Agrawal, Rani, Bruss, Matthew D, Granier, Sébastien, Wang, Yvonne L, Rasmussen, Søren G F, Horner, Kathleen, Wang, Ping, Lei, Tao, Patterson, Andrew J, Kobilka, Brian, Conti, Marco
Publicado em 2008

Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes

Por Haj Slimane, Zeineb, Bedioune, Ibrahim, Lechêne, Patrick, Varin, Audrey, Lefebvre, Florence, Mateo, Philippe, Domergue-Dupont, Valérie, Dewenter, Matthias, Richter, Wito, Conti, Marco, El-Armouche, Ali, Zhang, Jin, Fischmeister, Rodolphe, Vandecasteele, Grégoire
Publicado em 2014

Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporte...

Por Cazabat, Laure, Ragazzon, Bruno, Varin, Audrey, Potier-Cartereau, Marie, Vandier, Christophe, Vezzosi, Delphine, Risk-Rabin, Marthe, Guellich, Aziz, Schittl, Julia, Lechêne, Patrick, Richter, Wito, Nikolaev, Viacheslav O., Zhang, Jin, Bertherat, Jérôme, Vandecasteele, Grégoire
Publicado em 2014