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Signaling from β(1)- and β(2)-adrenergic receptors is defined by differential interactions with PDE4

β(1)- and β(2)-adrenergic receptors (βARs) are highly homologous, yet they play clearly distinct roles in cardiac physiology and pathology. Myocyte contraction, for instance, is readily stimulated by β(1)AR but not β(2)AR signaling, and chronic stimulation of the two receptors has opposing effects o...

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Bibliografski detalji
Glavni autori: Richter, Wito, Day, Peter, Agrawal, Rani, Bruss, Matthew D, Granier, Sébastien, Wang, Yvonne L, Rasmussen, Søren G F, Horner, Kathleen, Wang, Ping, Lei, Tao, Patterson, Andrew J, Kobilka, Brian, Conti, Marco
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196435/
https://ncbi.nlm.nih.gov/pubmed/18188154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601968
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