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Signaling from β(1)- and β(2)-adrenergic receptors is defined by differential interactions with PDE4
β(1)- and β(2)-adrenergic receptors (βARs) are highly homologous, yet they play clearly distinct roles in cardiac physiology and pathology. Myocyte contraction, for instance, is readily stimulated by β(1)AR but not β(2)AR signaling, and chronic stimulation of the two receptors has opposing effects o...
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Hoofdauteurs: | , , , , , , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Nature Publishing Group
2008
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2196435/ https://ncbi.nlm.nih.gov/pubmed/18188154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601968 |
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