Signaling from β(1)- and β(2)-adrenergic receptors is defined by differential interactions with PDE4

β(1)- and β(2)-adrenergic receptors (βARs) are highly homologous, yet they play clearly distinct roles in cardiac physiology and pathology. Myocyte contraction, for instance, is readily stimulated by β(1)AR but not β(2)AR signaling, and chronic stimulation of the two receptors has opposing effects o...

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Main Authors: Richter, Wito, Day, Peter, Agrawal, Rani, Bruss, Matthew D, Granier, Sébastien, Wang, Yvonne L, Rasmussen, Søren G F, Horner, Kathleen, Wang, Ping, Lei, Tao, Patterson, Andrew J, Kobilka, Brian, Conti, Marco
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196435/
https://ncbi.nlm.nih.gov/pubmed/18188154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601968
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