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Roles of GRK and PDE4 Activities in the Regulation of β(2) Adrenergic Signaling

An important focus in cell biology is understanding how different feedback mechanisms regulate G protein–coupled receptor systems. Toward this end we investigated the regulation of endogenous β(2) adrenergic receptors (β2ARs) and phosphodiesterases (PDEs) by measuring cAMP signals in single HEK-293...

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Detalhes bibliográficos
Main Authors: Xin, Wenkuan, Tran, Tuan M., Richter, Wito, Clark, Richard B., Rich, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279169/
https://ncbi.nlm.nih.gov/pubmed/18347080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709881
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