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A CaMKII/PDE4D negative feedback regulates cAMP signaling

cAMP production and protein kinase A (PKA) are the most widely studied steps in β-adrenergic receptor (βAR) signaling in the heart; however, the multifunctional Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is also activated in response to βAR stimulation and is involved in the regulation o...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Mika, Delphine, Richter, Wito, Conti, Marco
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343159/
https://ncbi.nlm.nih.gov/pubmed/25646485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419992112
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