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Critical Role of PDE4D in β(2)-Adrenoceptor-dependent cAMP Signaling in Mouse Embryonic Fibroblasts

One of the defining properties of β(2)-adrenergic receptor (β(2)AR) signaling is the transient and rapidly reversed accumulation of cAMP. Here we have investigated the contribution of different PDE4 proteins to the generation of this transient response. To this aim, mouse embryonic fibroblasts defic...

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Detalhes bibliográficos
Main Authors: Bruss, Matthew D., Richter, Wito, Horner, Kathleen, Jin, S.-L. Catherine, Conti, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504879/
https://ncbi.nlm.nih.gov/pubmed/18508768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803306200
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