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PDE4D and PDE4B Function in Distinct Subcellular Compartments in Mouse Embryonic Fibroblasts

Signaling through cAMP regulates most cellular functions. The spatiotemporal control of cAMP is, therefore, crucial for differential regulation of specific cellular targets. Here we investigated the consequences of PDE4B or PDE4D gene ablation on cAMP signaling at a subcellular level using mouse emb...

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Detalhes bibliográficos
Main Authors: Blackman, Brigitte E., Horner, Kathleen, Heidmann, Julia, Wang, Dan, Richter, Wito, Rich, Thomas C., Conti, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069460/
https://ncbi.nlm.nih.gov/pubmed/21288894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203604
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