PDE4 as a target for cognition enhancement

INTRODUCTION: The second messengers cAMP and cGMP mediate fundamental aspects of brain function relevant to memory, learning and cognitive functions. Consequently, cyclic nucleotide phosphodiesterases (PDEs), the enzymes that inactivate the cyclic nucleotides, are promising targets for the developme...

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Bibliografiske detaljer
Main Authors: Richter, Wito, Menniti, Frank S., Zhang, Han-Ting, Conti, Marco
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066988/
https://ncbi.nlm.nih.gov/pubmed/23883342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2013.818656
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