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PDE4 as a target for cognition enhancement
INTRODUCTION: The second messengers cAMP and cGMP mediate fundamental aspects of brain function relevant to memory, learning and cognitive functions. Consequently, cyclic nucleotide phosphodiesterases (PDEs), the enzymes that inactivate the cyclic nucleotides, are promising targets for the developme...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4066988/ https://ncbi.nlm.nih.gov/pubmed/23883342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2013.818656 |
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