Conserved expression and functions of PDE4 in rodent and human heart

PDE4 isoenzymes are critical in the control of cAMP signaling in rodent cardiac myocytes. Ablation of PDE4 affects multiple key players in excitation–contraction coupling and predisposes mice to the development of heart failure. As little is known about PDE4 in human heart, we explored to what exten...

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Bibliografske podrobnosti
Main Authors: Richter, Wito, Xie, Moses, Scheitrum, Colleen, Krall, Judith, Movsesian, Matthew A., Conti, Marco
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2010
Teme:
Original Contribution
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032896/
https://ncbi.nlm.nih.gov/pubmed/21161247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-010-0138-8
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