The Upstream Conserved Regions (UCRs) Mediate Homo- and Hetero-oligomerization of Type 4 Cyclic Nucleotide Phosphodiesterases (PDE4s)

Type 4 cyclic nucleotide phosphodiesterases (PDE4s) are divided into long and short forms by the presence or absence of conserved N-terminal domains termed upstream conserved regions (UCRs). We have shown previously that PDE4D2, a short variant, is a monomer, whereas PDE4D3, a long variant, is a dim...

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Gepubliceerd in:Biochem J
Hoofdauteurs: Xie, Moses, Blackman, Brigitte, Scheitrum, Colleen, Mika, Delphine, Blanchard, Elise, Lei, Tao, Conti, Marco, Richter, Wito
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315173/
https://ncbi.nlm.nih.gov/pubmed/24555506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131681
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