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Splice variants of the cyclic nucleotide phosphodiesterase PDE4D are differentially expressed and regulated in rat tissue

Cyclic nucleotide PDE4 (phosphodiesterase 4) inhibitors are being developed as potent anti-inflammatory drugs for use in chronic lung diseases, but the complexity of the PDE4 family has hampered this process. The four genes comprising the PDE4 family, PDE4A, PDE4B, PDE4C and PDE4D, are all expressed...

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Bibliografski detalji
Glavni autori: Richter, Wito, Jin, S.-L. Catherine, Conti, Marco
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183459/
https://ncbi.nlm.nih.gov/pubmed/15717866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050030
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