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Splice variants of the cyclic nucleotide phosphodiesterase PDE4D are differentially expressed and regulated in rat tissue

Cyclic nucleotide PDE4 (phosphodiesterase 4) inhibitors are being developed as potent anti-inflammatory drugs for use in chronic lung diseases, but the complexity of the PDE4 family has hampered this process. The four genes comprising the PDE4 family, PDE4A, PDE4B, PDE4C and PDE4D, are all expressed...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Richter, Wito, Jin, S.-L. Catherine, Conti, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183459/
https://ncbi.nlm.nih.gov/pubmed/15717866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050030
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