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Quantitative Modeling of GRK-Mediated β2AR Regulation
We developed a unified model of the GRK-mediated β2 adrenergic receptor (β2AR) regulation that simultaneously accounts for six different biochemical measurements of the system obtained over a wide range of agonist concentrations. Using a single deterministic model we accounted for (1) GRK phosphoryl...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798957/ https://ncbi.nlm.nih.gov/pubmed/20098494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000647 |
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