CREB-binding protein (CBP) regulates β-adrenoceptor (β-AR)−mediated apoptosis

Catecholamines regulate the β-adrenoceptor/cyclic AMP-regulated protein kinase A (cAMP/PKA) pathway. Deregulation of this pathway can cause apoptotic cell death and is implicated in a range of human diseases, such as neuronal loss during aging, cardiomyopathy and septic shock. The molecular mechanis...

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Autors principals: Lee, Y Y, Moujalled, D, Doerflinger, M, Gangoda, L, Weston, R, Rahimi, A, de Alboran, I, Herold, M, Bouillet, P, Xu, Q, Gao, X, Du, X-J, Puthalakath, H
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679460/
https://ncbi.nlm.nih.gov/pubmed/23579242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.29
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