Loading...

CREB-binding protein (CBP) regulates β-adrenoceptor (β-AR)−mediated apoptosis

Catecholamines regulate the β-adrenoceptor/cyclic AMP-regulated protein kinase A (cAMP/PKA) pathway. Deregulation of this pathway can cause apoptotic cell death and is implicated in a range of human diseases, such as neuronal loss during aging, cardiomyopathy and septic shock. The molecular mechanis...

Full description

Saved in:
Bibliographic Details
Main Authors: Lee, Y Y, Moujalled, D, Doerflinger, M, Gangoda, L, Weston, R, Rahimi, A, de Alboran, I, Herold, M, Bouillet, P, Xu, Q, Gao, X, Du, X-J, Puthalakath, H
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679460/
https://ncbi.nlm.nih.gov/pubmed/23579242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.29
Tags: Add Tag
No Tags, Be the first to tag this record!