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CREB-binding protein (CBP) regulates β-adrenoceptor (β-AR)−mediated apoptosis
Catecholamines regulate the β-adrenoceptor/cyclic AMP-regulated protein kinase A (cAMP/PKA) pathway. Deregulation of this pathway can cause apoptotic cell death and is implicated in a range of human diseases, such as neuronal loss during aging, cardiomyopathy and septic shock. The molecular mechanis...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679460/ https://ncbi.nlm.nih.gov/pubmed/23579242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.29 |
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