Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes

AIMS: The cAMP-dependent protein kinase (PKA) mediates β-adrenoceptor (β-AR) regulation of cardiac contraction and gene expression. Whereas PKA activity is well characterized in various subcellular compartments of adult cardiomyocytes, its regulation in the nucleus remains largely unknown. The aim o...

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Main Authors: Haj Slimane, Zeineb, Bedioune, Ibrahim, Lechêne, Patrick, Varin, Audrey, Lefebvre, Florence, Mateo, Philippe, Domergue-Dupont, Valérie, Dewenter, Matthias, Richter, Wito, Conti, Marco, El-Armouche, Ali, Zhang, Jin, Fischmeister, Rodolphe, Vandecasteele, Grégoire
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958623/
https://ncbi.nlm.nih.gov/pubmed/24550350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu029
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