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Characterization of the cyclic nucleotide phosphodiesterase subtypes involved in the regulation of the L-type Ca(2+) current in rat ventricular myocytes
1. The effects of several phosphodiesterase (PDE) inhibitors on the L-type Ca current (I(Ca)) and intracellular cyclic AMP concentration ([cAMP](i)) were examined in isolated rat ventricular myocytes. The presence of mRNA transcripts encoding for the different cardiac PDE subtypes was confirmed by R...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1999
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565993/ https://ncbi.nlm.nih.gov/pubmed/10369457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702506 |
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