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Role of cyclic nucleotide phosphodiesterase isoforms in cAMP compartmentation following β(2)-adrenergic stimulation of I(Ca,L) in frog ventricular myocytes
The role of cyclic nucleotide phosphodiesterase (PDE) isoforms in the β(2)-adrenergic stimulation of the L-type Ca(2+) current (I(Ca,L)) was investigated in frog ventricular myocytes using double patch-clamp and double-barrelled microperfusion techniques. Isoprenaline (ISO, 1 nM to 10 μM) was applie...
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| Päätekijät: | , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Blackwell Science Inc
2003
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2343164/ https://ncbi.nlm.nih.gov/pubmed/12815180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.045211 |
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