Characterization of the cyclic nucleotide phosphodiesterase subtypes involved in the regulation of the L-type Ca(2+) current in rat ventricular myocytes

1. The effects of several phosphodiesterase (PDE) inhibitors on the L-type Ca current (I(Ca)) and intracellular cyclic AMP concentration ([cAMP](i)) were examined in isolated rat ventricular myocytes. The presence of mRNA transcripts encoding for the different cardiac PDE subtypes was confirmed by R...

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Hauptverfasser: Verde, Ignacio, Vandecasteele, Grégoire, Lezoualc'h, Frank, Fischmeister, Rodolphe
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
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Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565993/
https://ncbi.nlm.nih.gov/pubmed/10369457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702506
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