The importance of occupancy rather than affinity of Ca(V)β subunits for the calcium channel I–II linker in relation to calcium channel function

Por Butcher, Adrian J, Leroy, Jérôme, Richards, Mark W, Pratt, Wendy S, Dolphin, Annette C
Publicado em 2006

A pocket on the surface of the N-terminal BRCT domain of Mcph1 is required to prevent abnormal chromosome condensation

Por Richards, Mark W., Leung, Justin W.C., Roe, S. Mark, Chen, Junjie, Bayliss, Richard
Publicado em 2009

Structural Basis of Poly(ADP-ribose) Recognition by the Multizinc Binding Domain of Checkpoint with Forkhead-associated and RING Domains (CHFR)

Por Oberoi, Jasmeen, Richards, Mark W., Crumpler, Simon, Brown, Nathan, Blagg, Julian, Bayliss, Richard
Publicado em 2010

Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugs

Por Bayliss, Richard, Choi, Jene, Fennell, Dean A., Fry, Andrew M., Richards, Mark W.
Publicado no Cell Mol Life Sci (2016)

A closed conformation of the Caenorhabditis elegans separase–securin complex

Por Bachmann, Gudrun, Richards, Mark W., Winter, Anja, Beuron, Fabienne, Morris, Edward, Bayliss, Richard
Publicado no Open Biol (2016)

Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain

Por Burgess, Selena G., Oleksy, Arkadiusz, Cavazza, Tommaso, Richards, Mark W., Vernos, Isabelle, Matthews, David, Bayliss, Richard
Publicado no Open Biol (2016)

Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors

Por Richards, Mark W., Burgess, Selena G., Poon, Evon, Carstensen, Anne, Eilers, Martin, Chesler, Louis, Bayliss, Richard
Publicado no Proc Natl Acad Sci U S A (2016)

Insights into the Conformational Variability and Regulation of Human Nek2 Kinase

Por Westwood, Isaac, Cheary, Donna-Marie, Baxter, Joanne E., Richards, Mark W., van Montfort, Rob L.M., Fry, Andrew M., Bayliss, Richard
Publicado em 2009

An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9

Por Richards, Mark W., O'Regan, Laura, Mas-Droux, Corine, Blot, Joelle M.Y., Cheung, Jack, Hoelder, Swen, Fry, Andrew M., Bayliss, Richard
Publicado em 2009

Coordination of adjacent domains mediates TACC3–ch-TOG–clathrin assembly and mitotic spindle binding

Por Hood, Fiona E., Williams, Samantha J., Burgess, Selena G., Richards, Mark W., Roth, Daniel, Straube, Anne, Pfuhl, Mark, Bayliss, Richard, Royle, Stephen J.
Publicado em 2013

Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical β-propeller domain

Por Richards, Mark W., Law, Edward W. P., Rennalls, La’Verne P., Busacca, Sara, O’Regan, Laura, Fry, Andrew M., Fennell, Dean A., Bayliss, Richard
Publicado em 2014

Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization

Por Haq, Tamanna, Richards, Mark W., Burgess, Selena G., Gallego, Pablo, Yeoh, Sharon, O'Regan, Laura, Reverter, David, Roig, Joan, Fry, Andrew M., Bayliss, Richard
Publicado no Nat Commun (2015)

Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression

Por O’Regan, Laura, Sampson, Josephina, Richards, Mark W., Knebel, Axel, Roth, Daniel, Hood, Fiona E., Straube, Anne, Royle, Stephen J., Bayliss, Richard, Fry, Andrew M.
Publicado no J Cell Biol (2015)

Molecular mechanisms of human IRE1 activation through dimerization and ligand binding

Por Joshi, Amar, Newbatt, Yvette, McAndrew, P. Craig, Stubbs, Mark, Burke, Rosemary, Richards, Mark W., Bhatia, Chitra, Caldwell, John J., McHardy, Tatiana, Collins, Ian, Bayliss, Richard
Publicado no Oncotarget (2015)