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The importance of occupancy rather than affinity of Ca(V)β subunits for the calcium channel I–II linker in relation to calcium channel function
The Ca(V)β subunits of voltage-gated calcium channels regulate the trafficking and biophysical properties of these channels. We have taken advantage of mutations in the tyrosine residue within the alpha interaction domain (AID) in the I–II linker of Ca(V)2.2 which reduce, but do not abolish, the bin...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1817768/ https://ncbi.nlm.nih.gov/pubmed/16627564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.109744 |
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