The importance of occupancy rather than affinity of Ca(V)β subunits for the calcium channel I–II linker in relation to calcium channel function

The Ca(V)β subunits of voltage-gated calcium channels regulate the trafficking and biophysical properties of these channels. We have taken advantage of mutations in the tyrosine residue within the alpha interaction domain (AID) in the I–II linker of Ca(V)2.2 which reduce, but do not abolish, the bin...

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Detalhes bibliográficos
Main Authors: Butcher, Adrian J, Leroy, Jérôme, Richards, Mark W, Pratt, Wendy S, Dolphin, Annette C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817768/
https://ncbi.nlm.nih.gov/pubmed/16627564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.109744
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