Functional exofacially tagged N-type calcium channels elucidate the interaction with auxiliary α(2)δ-1 subunits

Por Cassidy, John S., Ferron, Laurent, Kadurin, Ivan, Pratt, Wendy S., Dolphin, Annette C.
Publicado em 2014

The importance of occupancy rather than affinity of Ca(V)β subunits for the calcium channel I–II linker in relation to calcium channel function

Por Butcher, Adrian J, Leroy, Jérôme, Richards, Mark W, Pratt, Wendy S, Dolphin, Annette C
Publicado em 2006

Determinants of the voltage dependence of G protein modulation within calcium channel β subunits

Por Dresviannikov, Andriy V., Page, Karen M., Leroy, Jerôme, Pratt, Wendy S., Dolphin, Annette C.
Publicado em 2008

Genetic disruption of voltage-gated calcium channels in psychiatric and neurological disorders

Por Heyes, Samuel, Pratt, Wendy S., Rees, Elliott, Dahimene, Shehrazade, Ferron, Laurent, Owen, Michael J., Dolphin, Annette C.
Publicado no Prog Neurobiol (2015)

A Ca(V)2.1 N-terminal fragment relieves the dominant-negative inhibition by an Episodic ataxia 2 mutant

Por Dahimene, Shehrazade, Page, Karen M., Nieto-Rostro, Manuela, Pratt, Wendy S., D'Arco, Marianna, Dolphin, Annette C.
Publicado no Neurobiol Dis (2016)

The α(2)δ subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function

Por Davies, Anthony, Kadurin, Ivan, Alvarez-Laviada, Anita, Douglas, Leon, Nieto-Rostro, Manuela, Bauer, Claudia S., Pratt, Wendy S., Dolphin, Annette C.
Publicado em 2010

N Terminus Is Key to the Dominant Negative Suppression of Ca(V)2 Calcium Channels: IMPLICATIONS FOR EPISODIC ATAXIA TYPE 2

Por Page, Karen M., Heblich, Fay, Margas, Wojciech, Pratt, Wendy S., Nieto-Rostro, Manuela, Chaggar, Kanchan, Sandhu, Kieran, Davies, Anthony, Dolphin, Annette C.
Publicado em 2010

Calcium Currents Are Enhanced by α(2)δ-1 Lacking Its Membrane Anchor

Por Kadurin, Ivan, Alvarez-Laviada, Anita, Ng, Shu Fun Josephine, Walker-Gray, Ryan, D'Arco, Marianna, Fadel, Michael G., Pratt, Wendy S., Dolphin, Annette C.
Publicado em 2012

Differential upregulation in DRG neurons of an α(2)δ-1 splice variant with a lower affinity for gabapentin after peripheral sensory nerve injury

Por Lana, Beatrice, Schlick, Bettina, Martin, Stuart, Pratt, Wendy S., Page, Karen M., Goncalves, Leonor, Rahman, Wahida, Dickenson, Anthony H., Bauer, Claudia S., Dolphin, Annette C.
Publicado em 2014

The Stargazin-Related Protein γ7 Interacts with the mRNA-Binding Protein Heterogeneous Nuclear Ribonucleoprotein A2 and Regulates the Stability of Specific mRNAs, Including Ca(V)2....

Por Ferron, Laurent, Davies, Anthony, Page, Karen M., Cox, David J., Leroy, Jerôme, Waithe, Dominic, Butcher, Adrian J., Sellaturay, Priya, Bolsover, Steven, Pratt, Wendy S., Moss, Fraser J., Dolphin, Annette C.
Publicado em 2008

Proteolytic maturation of α(2)δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels

Por Kadurin, Ivan, Ferron, Laurent, Rothwell, Simon W, Meyer, James O, Douglas, Leon R, Bauer, Claudia S, Lana, Beatrice, Margas, Wojciech, Alexopoulos, Orpheas, Nieto-Rostro, Manuela, Pratt, Wendy S, Dolphin, Annette C
Publicado no eLife (2016)