Location, location, location…site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling

Por Tobin, Andrew B., Butcher, Adrian J., Kong, Kok Choi
Publicado em 2008

The importance of occupancy rather than affinity of Ca(V)β subunits for the calcium channel I–II linker in relation to calcium channel function

Por Butcher, Adrian J, Leroy, Jérôme, Richards, Mark W, Pratt, Wendy S, Dolphin, Annette C
Publicado em 2006

Three-dimensional Structure of Ca(V)3.1: COMPARISON WITH THE CARDIAC L-TYPE VOLTAGE-GATED CALCIUM CHANNEL MONOMER ARCHITECTURE

Por Walsh, Conor P., Davies, Anthony, Butcher, Adrian J., Dolphin, Annette C., Kitmitto, Ashraf
Publicado em 2009

Engineered Hyperphosphorylation of the β(2)-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization

Por Zindel, Diana, Butcher, Adrian J., Al-Sabah, Suleiman, Lanzerstorfer, Peter, Weghuber, Julian, Tobin, Andrew B., Bünemann, Moritz, Krasel, Cornelius
Publicado no Mol Pharmacol (2015)

N-Methyl-d-aspartate Receptors Mediate the Phosphorylation and Desensitization of Muscarinic Receptors in Cerebellar Granule Neurons

Por Butcher, Adrian J., Torrecilla, Ignacio, Young, Kenneth W., Kong, Kok Choi, Mistry, Sharad C., Bottrill, Andrew R., Tobin, Andrew B.
Publicado em 2009

Concomitant Action of Structural Elements and Receptor Phosphorylation Determines Arrestin-3 Interaction with the Free Fatty Acid Receptor FFA4

Por Butcher, Adrian J., Hudson, Brian D., Shimpukade, Bharat, Alvarez-Curto, Elisa, Prihandoko, Rudi, Ulven, Trond, Milligan, Graeme, Tobin, Andrew B.
Publicado em 2014

Differential G-protein-coupled Receptor Phosphorylation Provides Evidence for a Signaling Bar Code

Por Butcher, Adrian J., Prihandoko, Rudi, Kong, Kok Choi, McWilliams, Phillip, Edwards, Jennifer M., Bottrill, Andrew, Mistry, Sharad, Tobin, Andrew B.
Publicado em 2011

Identification of key phosphorylation sites in PTH1R that determine arrestin3 binding and fine-tune receptor signaling

Por Zindel, Diana, Engel, Sandra, Bottrill, Andrew R., Pin, Jean-Philippe, Prézeau, Laurent, Tobin, Andrew B., Bünemann, Moritz, Krasel, Cornelius, Butcher, Adrian J.
Publicado no Biochem J (2016)

Identification of phosphorylation sites in the COOH-terminal tail of the μ-opioid receptor

Por Chen, Ying-Ju, Oldfield, Sue, Butcher, Adrian J, Tobin, Andrew B, Saxena, Kunal, Gurevich, Vsevolod V, Benovic, Jeffrey L, Henderson, Graeme, Kelly, Eamonn
Publicado no J Neurochem (2012)

The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Ther...

Por Hudson, Brian D., Shimpukade, Bharat, Mackenzie, Amanda E., Butcher, Adrian J., Pediani, John D., Christiansen, Elisabeth, Heathcote, Helen, Tobin, Andrew B., Ulven, Trond, Milligan, Graeme
Publicado em 2013

Distinct phosphorylation sites on the ghrelin receptor, GHSR1a, establish a code that determines the functions of ß-arrestins

Por Bouzo-Lorenzo, Monica, Santo-Zas, Icía, Lodeiro, Maria, Nogueiras, Rubén, Casanueva, Felipe F., Castro, Marian, Pazos, Yolanda, Tobin, Andrew B, Butcher, Adrian J., Camiña, Jesús P.
Publicado no Sci Rep (2016)

The Stargazin-Related Protein γ7 Interacts with the mRNA-Binding Protein Heterogeneous Nuclear Ribonucleoprotein A2 and Regulates the Stability of Specific mRNAs, Including Ca(V)2....

Por Ferron, Laurent, Davies, Anthony, Page, Karen M., Cox, David J., Leroy, Jerôme, Waithe, Dominic, Butcher, Adrian J., Sellaturay, Priya, Bolsover, Steven, Pratt, Wendy S., Moss, Fraser J., Dolphin, Annette C.
Publicado em 2008

CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo

Por Rossi, Mario, Ruiz de Azua, Inigo, Barella, Luiz F., Sakamoto, Wataru, Zhu, Lu, Cui, Yinghong, Lu, Huiyan, Rebholz, Heike, Matschinsky, Franz M., Doliba, Nicolai M., Butcher, Adrian J., Tobin, Andrew B., Wess, Jürgen
Publicado no Proc Natl Acad Sci U S A (2015)

M(3)-muscarinic receptor promotes insulin release via receptor phosphorylation/arrestin-dependent activation of protein kinase D1

Por Kong, Kok Choi, Butcher, Adrian J., McWilliams, Phillip, Jones, David, Wess, Jürgen, Hamdan, Fadi F., Werry, Tim, Rosethorne, Elizabeth M., Charlton, Steven J., Munson, Sarah E., Cragg, Hannah A., Smart, Alison D., Tobin, Andrew B.
Publicado em 2010

An Antibody Biosensor Establishes the Activation of the M(1) Muscarinic Acetylcholine Receptor during Learning and Memory

Por Butcher, Adrian J., Bradley, Sophie J., Prihandoko, Rudi, Brooke, Simon M., Mogg, Adrian, Bourgognon, Julie-Myrtille, Macedo-Hatch, Timothy, Edwards, Jennifer M., Bottrill, Andrew R., Challiss, R. A. John, Broad, Lisa M., Felder, Christian C., Tobin, Andrew B.
Publicado no J Biol Chem (2016)

Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction

Por Bradley, Sophie J., Wiegman, Coen H., Iglesias, Max Maza, Kong, Kok Choi, Butcher, Adrian J., Plouffe, Bianca, Goupil, Eugénie, Bourgognon, Julie-Myrtille, Macedo-Hatch, Timothy, LeGouill, Christian, Russell, Kirsty, Laporte, Stéphane A., König, Gabriele M., Kostenis, Evi, Bouvier, Michel, Chung, Kian Fan, Amrani, Yassine, Tobin, Andrew B.
Publicado no Proc Natl Acad Sci U S A (2016)

M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

Por Bradley, Sophie J., Bourgognon, Julie-Myrtille, Sanger, Helen E., Verity, Nicholas, Mogg, Adrian J., White, David J., Butcher, Adrian J., Moreno, Julie A., Molloy, Colin, Macedo-Hatch, Timothy, Edwards, Jennifer M., Wess, Jurgen, Pawlak, Robert, Read, David J., Sexton, Patrick M., Broad, Lisa M., Steinert, Joern R., Mallucci, Giovanna R., Christopoulos, Arthur, Felder, Christian C., Tobin, Andrew B.
Publicado no J Clin Invest (2016)

The experimental power of FR900359 to study Gq-regulated biological processes

Por Schrage, Ramona, Schmitz, Anna-Lena, Gaffal, Evelyn, Annala, Suvi, Kehraus, Stefan, Wenzel, Daniela, Büllesbach, Katrin M., Bald, Tobias, Inoue, Asuka, Shinjo, Yuji, Galandrin, Ségolène, Shridhar, Naveen, Hesse, Michael, Grundmann, Manuel, Merten, Nicole, Charpentier, Thomas H., Martz, Matthew, Butcher, Adrian J., Slodczyk, Tanja, Armando, Sylvain, Effern, Maike, Namkung, Yoon, Jenkins, Laura, Horn, Velten, Stößel, Anne, Dargatz, Harald, Tietze, Daniel, Imhof, Diana, Galés, Céline, Drewke, Christel, Müller, Christa E., Hölzel, Michael, Milligan, Graeme, Tobin, Andrew B., Gomeza, Jesús, Dohlman, Henrik G., Sondek, John, Harden, T. Kendall, Bouvier, Michel, Laporte, Stéphane A., Aoki, Junken, Fleischmann, Bernd K., Mohr, Klaus, König, Gabriele M., Tüting, Thomas, Kostenis, Evi
Publicado no Nat Commun (2015)