CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo

G protein-coupled receptors (GPCRs) regulate virtually all physiological functions including the release of insulin from pancreatic β-cells. β-Cell M(3) muscarinic receptors (M3Rs) are known to play an essential role in facilitating insulin release and maintaining proper whole-body glucose homeostas...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Rossi, Mario, Ruiz de Azua, Inigo, Barella, Luiz F., Sakamoto, Wataru, Zhu, Lu, Cui, Yinghong, Lu, Huiyan, Rebholz, Heike, Matschinsky, Franz M., Doliba, Nicolai M., Butcher, Adrian J., Tobin, Andrew B., Wess, Jürgen
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2015
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679045/
https://ncbi.nlm.nih.gov/pubmed/26598688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519430112
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