Spinophilin as a novel regulator of M(3) muscarinic receptor-mediated insulin release in vitro and in vivo

Spinophilin (SPL), a multidomain scaffolding protein known to modulate the activity of different G-protein-coupled receptors, regulates various central nervous system (CNS) functions. However, little is known about the role of SPL expressed in peripheral cell types including pancreatic β cells. In t...

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Main Authors: Ruiz de Azua, Inigo, Nakajima, Ken-ichiro, Rossi, Mario, Cui, Yinghong, Jou, William, Gavrilova, Oksana, Wess, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado: Federation of American Societies for Experimental Biology 2012
Assuntos:
Research Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448777/
https://ncbi.nlm.nih.gov/pubmed/22730439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-204644
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