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RGS4 is a negative regulator of insulin release from pancreatic β-cells in vitro and in vivo
Therapeutic strategies that augment insulin release from pancreatic β-cells are considered beneficial in the treatment of type 2 diabetes. We previously demonstrated that activation of β-cell M(3) muscarinic receptors (M3Rs) greatly promotes glucose-stimulated insulin secretion (GSIS), suggesting th...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867926/ https://ncbi.nlm.nih.gov/pubmed/20385802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003655107 |
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