Intraislet glucagon signaling is critical for maintaining glucose homeostasis

Glucagon, a hormone released from pancreatic α cells, plays a key role in maintaining proper glucose homeostasis and has been implicated in the pathophysiology of diabetes. In vitro studies suggest that intraislet glucagon can modulate the function of pancreatic β cells. However, because of the lack...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Zhu, Lu, Dattaroy, Diptadip, Pham, Jonathan, Wang, Lingdi, Barella, Luiz F., Cui, Yinghong, Wilkins, Kenneth J., Roth, Bryan L., Hochgeschwender, Ute, Matschinsky, Franz M., Kaestner, Klaus H., Doliba, Nicolai M., Wess, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542600/
https://ncbi.nlm.nih.gov/pubmed/31012868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127994
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