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CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo
G protein-coupled receptors (GPCRs) regulate virtually all physiological functions including the release of insulin from pancreatic β-cells. β-Cell M(3) muscarinic receptors (M3Rs) are known to play an essential role in facilitating insulin release and maintaining proper whole-body glucose homeostas...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4679045/ https://ncbi.nlm.nih.gov/pubmed/26598688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519430112 |
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