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Location, location, location…site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling
It is now established that most of the ∼800 G-protein-coupled receptors (GPCRs) are regulated by phosphorylation in a process that results in the recruitment of arrestins, leading to receptor desensitization and the activation of arrestin-dependent processes. This generalized view of GPCR regulation...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Published By Elsevier In Association With The International Union Of Pharmacology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880250/ https://ncbi.nlm.nih.gov/pubmed/18606460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2008.05.006 |
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