Identification of key phosphorylation sites in PTH1R that determine arrestin3 binding and fine-tune receptor signaling

The parathyroid hormone receptor 1 (PTH1R) is a member of family B of G-protein-coupled receptors (GPCRs), predominantly expressed in bone and kidney where it modulates extracellular Ca(2+) homeostasis and bone turnover. It is well established that phosphorylation of GPCRs constitutes a key event in...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Zindel, Diana, Engel, Sandra, Bottrill, Andrew R., Pin, Jean-Philippe, Prézeau, Laurent, Tobin, Andrew B., Bünemann, Moritz, Krasel, Cornelius, Butcher, Adrian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103873/
https://ncbi.nlm.nih.gov/pubmed/27623777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160740
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