Ligand-induced internalization of the orexin OX(1) and cannabinoid CB(1) receptors assessed via N-terminal SNAP and CLIP-tagging

af Ward, Richard J, Pediani, John D, Milligan, Graeme
Udgivet 2011

Heteromultimerization of Cannabinoid CB(1) Receptor and Orexin OX(1) Receptor Generates a Unique Complex in Which Both Protomers Are Regulated by Orexin A

af Ward, Richard J., Pediani, John D., Milligan, Graeme
Udgivet 2011

Spatial Intensity Distribution Analysis: Studies of G Protein-Coupled Receptor Oligomerisation

af Pediani, John D., Ward, Richard J., Marsango, Sara, Milligan, Graeme
Udgivet i Trends Pharmacol Sci (2018)

Ligand Regulation of the Quaternary Organization of Cell Surface M(3) Muscarinic Acetylcholine Receptors Analyzed by Fluorescence Resonance Energy Transfer (FRET) Imaging and Homog...

af Alvarez-Curto, Elisa, Ward, Richard J., Pediani, John D., Milligan, Graeme
Udgivet 2010

Intramolecular Fluorescence Resonance Energy Transfer (FRET) Sensors of the Orexin OX(1) and OX(2) Receptors Identify Slow Kinetics of Agonist Activation

af Xu, Tian-Rui, Ward, Richard J., Pediani, John D., Milligan, Graeme
Udgivet 2012

Regulation of Oligomeric Organization of the Serotonin 5-Hydroxytryptamine 2C (5-HT(2C)) Receptor Observed by Spatial Intensity Distribution Analysis

af Ward, Richard J., Pediani, John D., Godin, Antoine G., Milligan, Graeme
Udgivet i J Biol Chem (2015)

Dynamic Regulation of Quaternary Organization of the M(1) Muscarinic Receptor by Subtype-selective Antagonist Drugs

af Pediani, John D., Ward, Richard J., Godin, Antoine G., Marsango, Sara, Milligan, Graeme
Udgivet i J Biol Chem (2016)

Spatial intensity distribution analysis quantifies the extent and regulation of homodimerization of the secretin receptor

af Ward, Richard J., Pediani, John D., Harikumar, Kaleeckal G., Miller, Laurence J., Milligan, Graeme
Udgivet i Biochem J (2017)

A Molecular Basis for Selective Antagonist Destabilization of Dopamine D(3) Receptor Quaternary Organization

af Marsango, Sara, Caltabiano, Gianluigi, Jiménez-Rosés, Mireia, Millan, Mark J., Pediani, John D., Ward, Richard J., Milligan, Graeme
Udgivet i Sci Rep (2017)

The protein kinase C inhibitor, Ro-31-7459, is a potent activator of ERK and JNK MAP kinases in HUVECs and yet inhibits cyclic AMP-stimulated SOCS-3 gene induction through inactiva...

af Wiejak, Jolanta, Dunlop, Julia, Stoyle, Chloe, Lappin, Gillian, McIlroy, Anna, Pediani, John D., Gao, Shan, Yarwood, Stephen J.
Udgivet 2012

A general method to quantify ligand-driven oligomerization from fluorescence-based images

af Stoneman, Michael R., Biener, Gabriel, Ward, Richard J., Pediani, John D., Badu, Dammar, Eis, Annie, Popa, Ionel, Milligan, Graeme, Raicu, Valerică
Udgivet i Nat Methods (2019)

Chemokine receptor CXCR4 oligomerization is disrupted selectively by the antagonist ligand IT1t

af Ward, Richard J., Pediani, John D., Marsango, Sara, Jolly, Richard, Stoneman, Michael R., Biener, Gabriel, Handel, Tracy M., Raicu, Valerică, Milligan, Graeme
Udgivet i J Biol Chem (2020)

Developing Chemical Genetic Approaches to Explore G Protein-Coupled Receptor Function: Validation of the Use of a Receptor Activated Solely by Synthetic Ligand (RASSL)

af Alvarez-Curto, Elisa, Prihandoko, Rudi, Tautermann, Christofer S., Zwier, Jurriaan M., Pediani, John D., Lohse, Martin J., Hoffmann, Carsten, Tobin, Andrew B., Milligan, Graeme
Udgivet 2011

The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Ther...

af Hudson, Brian D., Shimpukade, Bharat, Mackenzie, Amanda E., Butcher, Adrian J., Pediani, John D., Christiansen, Elisabeth, Heathcote, Helen, Tobin, Andrew B., Ulven, Trond, Milligan, Graeme
Udgivet 2013

Novel Role for Proteinase-activated Receptor 2 (PAR(2)) in Membrane Trafficking of Proteinase-activated Receptor 4 (PAR(4))

af Cunningham, Margaret R., McIntosh, Kathryn A., Pediani, John D., Robben, Joris, Cooke, Alexandra E., Nilsson, Mary, Gould, Gwyn W., Mundell, Stuart, Milligan, Graeme, Plevin, Robin
Udgivet 2012