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Heteromultimerization of Cannabinoid CB(1) Receptor and Orexin OX(1) Receptor Generates a Unique Complex in Which Both Protomers Are Regulated by Orexin A

Agonist-induced internalization was observed for both inducible and constitutively expressed forms of the cannabinoid CB(1) receptor. These were also internalized by the peptide orexin A, which has no direct affinity for the cannabinoid CB(1) receptor, but only when the orexin OX(1) receptor was co-...

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Autors principals: Ward, Richard J., Pediani, John D., Milligan, Graeme
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199489/
https://ncbi.nlm.nih.gov/pubmed/21908614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.287649
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