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Heteromultimerization of Cannabinoid CB(1) Receptor and Orexin OX(1) Receptor Generates a Unique Complex in Which Both Protomers Are Regulated by Orexin A

Agonist-induced internalization was observed for both inducible and constitutively expressed forms of the cannabinoid CB(1) receptor. These were also internalized by the peptide orexin A, which has no direct affinity for the cannabinoid CB(1) receptor, but only when the orexin OX(1) receptor was co-...

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Detalhes bibliográficos
Main Authors: Ward, Richard J., Pediani, John D., Milligan, Graeme
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199489/
https://ncbi.nlm.nih.gov/pubmed/21908614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.287649
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