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Toward the Development of Bivalent Ligand Probes of Cannabinoid CB1 and Orexin OX1 Receptor Heterodimers
[Image: see text] Cannabinoid CB1 and orexin OX1 receptors have been suggested to form heterodimers and oligomers. Aimed at studying these complexes, a series of bivalent CB1 and OX1 ligands combining SR141716 and ACT-078573 pharmacophores were designed, synthesized, and tested for activity against...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060943/ https://ncbi.nlm.nih.gov/pubmed/24944734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4004759 |
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