Amiodarone and its Putative Metabolites Fail to Activate Wild Type hTAAR1

Por Lewin, Anita H., Navarro, Hernán A., Gilmour, Brian P.
Publicado em 2009

Inhibition of NFκB by the natural product Withaferin A in cellular models of Cystic Fibrosis inflammation

Por Maitra, Rangan, Porter, Melissa A, Huang, Shan, Gilmour, Brian P
Publicado em 2009

Toward the Development of Bivalent Ligand Probes of Cannabinoid CB1 and Orexin OX1 Receptor Heterodimers

Por Perrey, David A., Gilmour, Brian P., Thomas, Brian F., Zhang, Yanan
Publicado em 2014

Identifying Structural Features on 1,1-Diphenyl-hexahydro-oxazolo[3,4-a]pyrazin-3-ones Critical For Neuropeptide S Antagonist Activity

Por Zhang, Yanan, Gilmour, Brian P., Navarro, Hernán A., Runyon, Scott P.
Publicado no Bioorg Med Chem Lett (2008)

Diaryl urea analogues of SB-334867 as orexin-1 receptor antagonists

Por Perrey, David A., Gilmour, Brian P., Runyon, Scott P., Thomas, Brian F., Zhang, Yanan
Publicado em 2011

Truncated Orexin Peptides: Structure–Activity Relationship Studies

Por German, Nadezhda A., Decker, Ann M., Gilmour, Brian P., Thomas, Brian F., Zhang, Yanan
Publicado em 2013

Preparation of a Series of 5-Methyl-3-(substituted)-[1,2,4]triazines

Por Gichinga, Moses G., Olson, Jeremy P., Butala, Elizabeth, Gilmour, Brian P., Navarro, Hernán H., Carroll, F. Ivy
Publicado em 2011

Synthesis and Evaluation of Metabotropic Glutamate Receptor Subtype 5 Antagonists Based on Fenobam

Por Gichinga, Moses G., Olson, Jeremy P., Butala, Elizabeth, Navarro, Hernán A., Gilmour, Brian P., Mascarella, S. Wayne, Carroll, F. Ivy
Publicado em 2011

Diarylureas as Allosteric Modulators of the Cannabinoid CB1 Receptor: Structure–Activity Relationship Studies on 1-(4-Chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}ure...

Por German, Nadezhda, Decker, Ann M., Gilmour, Brian P., Gay, Elaine A., Wiley, Jenny L., Thomas, Brian F., Zhang, Yanan
Publicado em 2014

Substituted Tetrahydroisoquinolines as Selective Antagonists for the Orexin 1 Receptor

Por Perrey, David A., German, Nadezhda A., Gilmour, Brian P., Li, Jun-Xu, Harris, Danni L., Thomas, Brian F., Zhang, Yanan
Publicado em 2013

The Importance of the 6- and 7-Positions of Tetrahydroisoquinolines as Selective Antagonists for the Orexin 1 Receptor

Por Perrey, David A., Decker, Ann M., Li, Jun-Xu, Gilmour, Brian P., Thomas, Brian F., Harris, Danni L., Runyon, Scott P., Zhang, Yanan
Publicado no Bioorg Med Chem (2015)

Synthesis, Pharmacological Characterization, and Structure–Activity Relationship Studies of Small Molecular Agonists for the Orphan GPR88 Receptor

Por Jin, Chunyang, Decker, Ann M., Huang, Xi-Ping, Gilmour, Brian P., Blough, Bruce E., Roth, Bryan L., Hu, Yang, Gill, Joseph B., Zhang, X. Peter
Publicado em 2014

The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the Neurotensin receptor type 2

Por Thomas, James B., Giddings, Angela M., Olepu, Srinivas, Wiethe, Robert W., Warner, Keith R., Sarret, Philippe, Longpre, Jean-Michel, Runyon, Scott P., Gilmour, Brian P
Publicado no Bioorg Med Chem Lett (2015)

A New Synthesis of the ORL-1 Antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and Activity in a Calcium...

Por Smith, Emilie D., Vinson, N. Ariane, Zhong, Desong, Berrang, Bertold D., Catanzaro, Jennifer L., Thomas, James B., Navarro, Hernán A., Gilmour, Brian P., Deschamps, Jeffrey, Carroll, F. Ivy
Publicado em 2007

Discovery of N-{4-[(3-Hydroxyphenyl)-3-methylpiperazin-1-yl]methyl-2-methylpropyl}-4-phenoxybenzamide Analogues as Selective Kappa Opioid Receptor Antagonists

Por Kormos, Chad M., Jin, Chunyang, Cueva, Juan Pablo, Runyon, Scott P, Thomas, James B., Brieaddy, Lawrence E., Mascarella, S. Wayne, Navarro, Hernán A., Gilmour, Brian P., Carroll, F. Ivy
Publicado em 2013

Effect of 1-Substitution on Tetrahydroisoquinolines as Selective Antagonists for the Orexin-1 Receptor

Por Perrey, David A., German, Nadezhda A., Decker, Ann M., Thorn, David, Li, Jun-Xu, Gilmour, Brian P., Thomas, Brian F., Harris, Danni L., Runyon, Scott P., Zhang, Yanan
Publicado no ACS Chem Neurosci (2015)

Effect of the 3- and 4-Methyl Groups on the Opioid Receptor Properties of N-Substituted trans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines

Por Kormos, Chad M., Cueva, Juan Pablo, Gichinga, Moses G., Runyon, Scott P., Thomas, James B., Brieaddy, Lawrence E., Mascarella, S. Wayne, Gilmour, Brian P., Navarro, Hernán A., Carroll, F. Ivy
Publicado em 2014

Identification of N-[(5-{[(4-Methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl]-l-leucine (NTRC-824), a Neurotensin-like Nonpeptide Compound Selective for the N...

Por Thomas, James B., Giddings, Angela M., Wiethe, Robert W., Olepu, Srinivas, Warner, Keith R., Sarret, Philippe, Gendron, Louis, Longpre, Jean-Michel, Zhang, Yanan, Runyon, Scott P., Gilmour, Brian P.
Publicado em 2014

Identification of 1-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane Carboxylic Acid as a Selective Nonpeptide Neurotensin Receptor Type 2 Compo...

Por Thomas, James B., Giddings, Angela M., Wiethe, Robert W., Olepu, Srinivas, Warner, Keith R., Sarret, Philippe, Gendron, Louis, Longpre, Jean-Michel, Zhang, Yanan, Runyon, Scott P., Gilmour, Brian P.
Publicado no J Med Chem (2014)

Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-L-leucine (NTRC-808), a novel nonpeptide chemotype selective for the Neurotensin receptor type 2

Por Thomas, James B., Giddings, Angela M., Olepu, Srinivas, Wiethe, Robert W., Harris, Danni L., Narayanan, Sanju, Warner, Keith R., Sarret, Philippe, Longpre, Jean-Michel, Runyon, Scott P., Gilmour, Brian P.
Publicado no Bioorg Med Chem Lett (2014)