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Amiodarone and its Putative Metabolites Fail to Activate Wild Type hTAAR1

The ability of amiodarone and its putative metabolites to activate unmodified human trace amine associated receptor 1 (hTAAR1) stably expressed in CHO cell lines was evaluated. Receptor activation was monitored by measuring the accumulation of cAMP, the putative hTAAR1 native second messenger, or ca...

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Autori principali: Lewin, Anita H., Navarro, Hernán A., Gilmour, Brian P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789647/
https://ncbi.nlm.nih.gov/pubmed/19740654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.08.058
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