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Warfarin-Amiodarone Drug-Drug Interactions: Determination of [I](u)/K(I),(u) for Amiodarone and its Plasma Metabolites

A retrospective clinical evaluation in a cohort of 73 patients receiving stable anticoagulation therapy showed that the addition/elimination of amiodarone resulted in a 6–65% change in warfarin dose requirement. To evaluate the roles of amiodarone and its circulating metabolites in this highly varia...

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Detalhes bibliográficos
Main Authors: McDonald, MG, Au, NT, Wittkowsky, AK, Rettie, AE
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900249/
https://ncbi.nlm.nih.gov/pubmed/22398967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2011.283
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