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Interaction of the anticoagulant drug warfarin and its metabolites with human plasma albumin

The interaction of the anticoagulant drug warfarin and its metabolites with human plasma albumin was studied by equilibrium dialysis. A 20-fold variation of buffer ionic strength (0.017-0.340) caused no significant change in the warfarin association constant. But the binding strength rose significan...

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Détails bibliographiques
Auteur principal: O'Reilly, Robert A.
Format: Artigo
Langue:Inglês
Publié: 1969
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC322205/
https://ncbi.nlm.nih.gov/pubmed/5765021
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