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Interaction of the anticoagulant drug warfarin and its metabolites with human plasma albumin

The interaction of the anticoagulant drug warfarin and its metabolites with human plasma albumin was studied by equilibrium dialysis. A 20-fold variation of buffer ionic strength (0.017-0.340) caused no significant change in the warfarin association constant. But the binding strength rose significan...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Autor principal: O'Reilly, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1969
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322205/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5765021/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105968
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