Stereoselective Interaction of Phenylbutazone with [(12)C/(13)C]Warfarin Pseudoracemates in Man

To evaluate the interaction of phenylbutazone with racemic warfarin or R,S-(±)-warfarin in man, S-(−)-warfarin or levowarfarin was synthesized with (13)C label in the 2-position of the coumarin nucleus and added to [(12)C]R(+)-warfarin or dextrowarfarin to form a [(12)C/(13)C]pseudoracemate of warfa...

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Pubblicato in:	J Clin Invest
Autori principali:	O'Reilly, Robert A., Trager, William F., Motley, Catherine H., Howald, William
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1980
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371418/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7354137/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109722
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